MTHFR, APOE, COMT, FADS2, VDR — your genes determine which supplements you actually need. This cheat sheet covers 20 of the most clinically actionable SNPs with rs numbers, biological impact, and exact supplement protocols for each variant. Listen ⇢

Not all supplement forms are equal. This guide compares glycinate, citrate, oxide, liposomal, and methylated forms using published absorption evidence. Listen ⇢

The cheapest supplement is often the most expensive once you factor in absorption. This database calculates the true cost per mg absorbed for 40+ supplements — showing where cheap forms like magnesium oxide and standard curcumin are terrible value. Listen ⇢

A research synthesis of 6 real randomized controlled trials plus 1 meta-analysis on nicotinamide riboside (NR) — NAD+ elevation, dosage, and how NR compares to NMN in actual human data. Listen ⇢

Most supplement labels show milligrams — but milligrams don’t equal absorption. Magnesium oxide absorbs at just 4% while glycinate hits 80%. Get the real absorption percentages for iron, magnesium, calcium, CoQ10, curcumin, vitamin D, and B12 forms. Listen ⇢

A research synthesis of 7 real randomized controlled trials and meta-analyses on NMN (nicotinamide mononucleotide) supplementation — what happens to NAD+ levels, physical function, and metabolic markers. Listen ⇢

Which supplements are safe during pregnancy — and which ones could harm your baby? This database classifies 50+ supplements as Safe, Caution, Avoid, or Insufficient Data for each trimester and breastfeeding, based on FDA, Cochrane, and LactMed evidence. Listen ⇢

Quick Answer Animal studies demonstrate that spermidine reliably triggers autophagy and extends lifespan in yeast, nematodes, flies, and mice, yet human data remain limited to one observational cohort linking higher dietary intake to reduced mortality and small randomized trials whose primary endpoints have not shown clear benefits. No formal meta-analysis… Listen ⇢